The current launched vaccine by Pfizer-BioNTech and Moderna proved to be successful in preventing 50% of cases; however, a dilemma in curtailing the transmission of the SARS COV still thrives. The vaccination has two sole purposes; prevention of the disease and immunological. Despite the limited public health data to determine the outcomes of COVID vaccines, the situation provides an opportunity to explore the unique process of immunological development.
Literature defines that the injected vaccines stimulate the immune system and prepares the antibodies against the virus. Nevertheless, COVID 19 vaccines only trigger a specific class of immunoglobulins known as IgG. Matthew Woodruff, an immunologist at Emory University explained, “on contact with foreign entities IgG is swiftly produced especially in deeper parts of the body such as muscles and blood.”
Above all, a new class of immunoglobulins, IgAwas discovered to play a pivotal role in COVID transmission. These immunoglobulins protect over the mucosal surfaces such as the nose, throat, lungs, and digestive tract. Thus, the immune system developed facilitates to maintain the internal environment to the external dynamics.
Woodruff expressed, “after the patient recovers from the COVID infection, the respiratory tract is filled with IgA, which prevents the re-infection and transmission.”
Many scientists fear the time taken to address the concerns regarding the adverse effects of vaccines. Therefore, they believe to vaccinate each with at least two doses within an intermittent period of two weeks to initiate maximum immunity. Thereby, enabling the public health officers to take earlier action against uncertainty.
In recent reports, emergencyvaccines (Moderna, Pfizer-BioNTech, and AstraZeneca)granted to western countries have shown high efficacy in phase 3 clinical trials. Meanwhile,the Sinopharm and Sinovac vaccines from China and the Bharat Biotech vaccine in India are underprocess for approval.
The safety precaution should be carried out despite vaccination as it is a slow process.