The Probiotic and Postbiotic Bacteria Sought Potential Against Multi Drug Resistance Bacteria

The rising problem of bacterial resistance against standard drug treatment has become a conduit for the spread of infectious diseases. The study published in the Journal of Infection in a Developing Country emphasized the deteriorating conditions of the suffering patients and timely potency loss of the antibiotics.

The lead author, Nazar Hussain commented, “ food transmission is a common pathway perceived for disseminating the microbial infection especially salmonella species.” In Pakistan, 60 % of the population suffers from lactose intolerance due to the limited activity of lactase in the intestine. Many of the symptoms are manageable using simple medication and therapy. However, medical literature revealed that with genetic alteration more than 75% of the population present with reduced lactase activity. Thus, increasing intake of drugs has led to bacterial Multi-Drug Resistance (MDR) across the world.

Among the 32 strains of lactic acid bacteria (LAB) collected from the diary source, the majority reported presenting with a high prevalence of MDR in Pakistan. The team identified, “  the study investigates in accordance with only 4 types of probiotic strains which included, Weissellaconfusa PL6, Enterococcus faecium PL7, and Lactobacillus delbrueckii PL11 and PL13. These bacterias exhibited superior efficacy in degrading lactose with susceptibility to the standard antibiotics”Nevertheless, unlike Ent. faecium,  to verify the efficiency of W. confusa probiotics, it needs to be tested empirically at the strain level.

The author reported, “these 4 probiotics were identified to ferment lactose and produce lactic acid, which inhibited the activity of the MDR. In addition, the postbiotics proved to be effective in boosting the probiotic activity and overcome the drawbacks of the probiotics as well.” Therefore, to reduce the incidence of drug resistance, scientists recommend the use of probiotics and postbiotics to improve the body’s immunity along with the added nutritional value.

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